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The BHN97Δ ftsY vaccine prevented mortality in this synergistic model of secondary bacterial infection (Fig 6C).
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In this manuscript, it is proposed that both mechanistic models should be merged into a single one: the synergistic model.
Given the advantages of the synergistic model, it is proposed that it will provide the basis to fully understand the complex nature of IDP binding.
In the synergistic model, ERβ overexpression enhances E2 response, whereas in the attenuation model, ERβ diminishes the observed E2-regulated gene expression.
This finding is consistent with a synergistic model whereby inflammation may lower the threshold for pain reporting in individuals with increased vulnerability for somatic symptom reporting.
So our motivation in this paper is to develop a new video tone mapping operator (TMO) based on a synergistic model of the retina.
Design consideration involved extensive simulation experiments to select input representation based on raw data and statistical features, artificial neural network recognizer design based on synergistic model, and monitoring diagnosis approach based on two-stage technique.
Enzymolysis and ultrasonication that were simultaneously conducted was selected as the UAEE synergistic model and the optimum extraction conditions with a maximum polysaccharide yield of 4.33 ± 0.15% were as follows: extraction temperature, 51.5 °C; ultrasonic power, 440 W; pH, 5.0; liquid-to-material ratio, 5.70 1 mL/g; and extraction time, 20 min.
Interestingly, a two-step synergistic model was proposed to explain the interaction and activity of progesterone receptor and NFI [45].
This results in both sexual and aggressive deficits even though two-thirds of the VNO remains unperturbed, further supporting a synergistic model of pheromone signaling.
This is not surprising given X2 tendency to over predict synergistic models [ 24].
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