Sentence examples for this substantial challenge from inspiring English sources

This substantial challenge to energy metabolic pathways made apparent the benefit of the more diverse formulation in CytoMax, which includes PolyLactate.

In conclusion, this study revealed the substantial challenges associated with implementing a fully self-directed intervention in an adolescent sample.

This presented a substantial challenge in further educating participants about healthy eating and dietary changes.

This is a substantial challenge for those who design and provide information.

This also represents a substantial challenge to correlate validated toxicity end points including induced gene expression.

However this technology is facing substantial challenge from the need to reduce costs and/or increase performance.

The use of tissue penetrant near-IR wavelengths enables in vivo applications, however the design of molecules that function in this range remains a substantial challenge.

While the benefits of exercise-based cardiac rehabilitation in the secondary prevention of coronary heart disease are well established [8 10], the complex nature of this intervention presents a substantial challenge to its implementation.

This also poses a substantial challenge in the detailed structural characterization of Cby.

The HLA system is the most polymorphic of all human genetic systems and this diversity raises a substantial challenge in the identification of matched donors.

This will be a substantial challenge in particular for Southern and Eastern Europe, including Russia, where HCV prevalence and incidence rates are high.