Sentence examples for this substantial advance from inspiring English sources

"Not only was there this substantial advance, but Random House had a big publicity machine".

Despite this substantial advance, the advantages of this vertebrate model to decipher the role of telomerase in regeneration, aging and cancer have only been partially exploited.

If the hypothesis were proven true this would be a substantial advance for this field and for clinical cardiology The conclusions are sensible and justified.

This represents a substantial advance over front-end findings, doubling the percent of people who understood the Tree as a scientific construct.

Despite the substantial advances documented in the UN enrollment report, the findings were pessimistic about attaining universal education by 2015.

What is striking about Miliband's proposals is not their radicalism, but their timidity compared with the substantial advances the coalition has made under the city deals programme.

This study represents a substantial advance and emphasises the potential for bioengineered organ replacement in future regenerative therapies".

Secondly, this approach represents a substantial advance over previous methods of using EEG or MEG data to look at functional connectivity.

This report represents a substantial advance in our understanding of the genome wide effects triggered by "passive sensitization" or active stimulation of human mast cells, supporting mast cells' potential involvement in a wide range of inflammatory responses.

If one could show that specific genomic rearrangements in plasma DNA provide a sensitive and specific measure of tumor growth rate and that they can be used as an early biomarker of disease prognosis and patient outcome, this may provide a substantial advance in monitoring the disease burden in patients with CRC.

This result is a substantial advance on previously available laboratory data regarding intraspinal olfactory cell transplantation because it establishes that the beneficial effects are sufficiently robust to be detectable even in clinical cases, in which the 'noise' of other uncontrolled variables, such as precise character of the injury, makes an effect more difficult to detect.