Sentence examples for this substantial activity from inspiring English sources

This substantial activity is unlikely due to tubulin-assembly, however, since these compounds are 120 200-fold less potent than paclitaxel, and most of the remaining compounds are at least 120 200-folds potent.

Pinto et al (2007) were the first to study cetuximab in combination with irinotecan and 5-fluorouracil in this setting and recorded a response rate of 44% with a 95% CI ranging from 28 to 61%, thus indicating the substantial activity of this regimen.

However, this peptide had no substantial activity against MRSA, E. coli ESBL, or VREF (Fig.  4a).

In this case, the compounds display substantial activity, especially the sulfur-containing substituted 1,2-benzisothiazoles.

A phase II trial of bevacizumab plus erlotinib revealed substantial activity of this combination in patients treated previously or patients who had not received treatment because of the presence of poor-prognostic features (Hainsworth et al, 2007).

This investigation has shown that AP is present in substantial activity in bovine NS.

In this population of locally advanced oesophageal SCC patients, DCF showed substantial activity in the treatment of oesophageal cancer.

This has in a sense of a "no regret policy" triggered substantial activity worldwide to decrease emission of greenhouse gases, especially of CO2, and various attempts have been made to set binding limits for the emission of these gases.

All the works included substantial activity for at least one percussionist.

Whilst clearly we predicted and prepared for substantial activity in Royal Mail shares, the volumes involved have gone off any conventional scale.

"We still don't quite understand the Oct. 31 date, since substantial activity has occurred since," Mr. Koutoulas asks.