Sentence examples for this subsequently activates from inspiring English sources

It is composed of a unique p19 subunit and a common p40 subunit sharing with IL-12 4. IL-23 binds to a heterodimeric receptor composed of the IL-12 receptor β1 (IL-12Rβ1) and IL-23 receptor (IL-23R) and this subsequently activates Jak2, Tyk2, and signal transducers and activators of transcription (STATs) 1, 3, 4, and 5 5.

This subsequently activates downstream caspases and by sequestering the antiapoptotic protein Bcl-2.

These steroids bind to their receptor, activating hormone response elements and gene transcription; this subsequently activates hormone response proteins that influence cell function and differentiation (Clark et al 2002).

This event subsequently activates p38 MAPK, which becomes phosphorylated.

This binding subsequently activates a tyrosine kinase intracellular signaling cascade stimulating IL-1β, TNF-α and ROS production (Bamberger et al., 2003).

In addition to MyD88 pathway, stimulation of TLR4 also activates MyD88 independent TIR-domain containing adapter-inducing interferon- β (TRIF) pathway where TRIF links to interferon regulatory factor-3 (IRF3) which induces interferon- β secretion, and this cytokine subsequently activates a series of genes that regulate host protection [ 37, 57].

The DNA-binding domain senses DNA breaks and subsequently activates PARP-1 activity [ 19].

Activated TAK1 subsequently activates the mitogen-activated protein kinase (MAPK) and NF- κB pathways, which together drive the transcription of pro-inflammatory and anti-apoptotic genes.