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All BMPs tested in this study stimulated R-Smad phosphorylation, to similar levels, in WEHI 274.1 cells (see Figure S2B), suggesting the differential ability of some BMPs to stimulate chemotaxis is not imparted by selective activation of R-Smads.
In this study, stimulated FOXP3 expression did correlate with in vitro proliferation of both CD4+ and CD8+ T cells to anti-CD3 stimulation but there was no correlation between expression of FOXP3 and the activation marker CD25.
The fungal polysaccharide fractions tested in this study stimulated macrophage production of cytokines at a higher level.
Encouraging results obtained from this study stimulated researchers to conduct a vast number of clinical trials to confirm the clinical efficacy of tretinoin in the treatment of photoaging.
The results of this study stimulated the initiation of additional testing of OPP for both tumor induction and possible reactivity with DNA.
Experiments using TLR7 deficient mouse cells confirmed that all the conjugates used in this study stimulated immune responses exclusively through TLR7.
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This study stimulates further work on the potential use of this synthetic biodegradable PCL nerve conduit in a clinical setting.
Data generated from this study, stimulate further functional investigations on the predicted target genes and pathways involved in the biological effect of human adult stem cells.
The results obtained in this study stimulate further detailed biochemical, molecular, chromatographic, and spectrometric analyses.
In this study, optically stimulated luminescence (OSL) and radiocarbon dating techniques were successfully applied to date these terrace systems.
The negative finding from this study has stimulated ongoing studies of other potential mediators, e.g. stress hormones.
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