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a history of severe adverse reaction or known hypersensitivity to maltose and/or silicon dioxide; patients requiring hospitalization; use of any investigational drug and/or participation in any clinical trial within 3 months before entering this study; inability to give a valid written informed consent or to properly follow the protocol.
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Key limitations of this study included inability to capture seasonal variations in illness patterns during the 4-week study period or regional variation due to the close proximity of study hospitals to one another, the likely impact of the concurrent outbreak of EV-71, and lack of data collected on weekends and overnight.
There were two main limitations of this study: the inability to audio-record the interviews and the generalizability of the results.
In this study, the inability to get enough and/or quality food was about 2.1 times higher in the non-adherent group which shows a significant association with non-adherence to ART.
Although significant efforts were made in order to select target genes with highest discriminatory power between sensitizers and non-sensitizers in this study, the inability to accurately classify weak sensitizers on the evaluated platforms could potentially be an artifact generated by the smaller number of genes included in this study (n =28) in comparison to the complete GARD signature (n = 200).
37 A fourth limitation of this study was its inability to test the feasibility of study logistics for a randomised clinical trial (eg, recruitment rate, dropout rate and issues concerning randomisation).
Another limitation of this study is the inability to adjust for PM2.5, as other studies observed strong associations with AMI [ 12].
Limitations of this study include the inability to establish temporality (given the cross-sectional study design) and the inability to evaluate individual pesticides or account for factors related to blood pressure such as prenatal toxicant exposures, concurrent and previous dietary patterns (e.g., salt and fat consumption), and perinatal health history.
Qualitative interviews indicated that career women and full-time homemakers were reluctant to participate in this study for an inability to comply with the needs and schedule of the study.
The major limitation of this study is the inability to evaluate the hepatitis B core antibody (antiHBc) in our study population due to low budget and limited resources.
Since the aqueous extract of Piper sarmentosum leaves used in the present study was not a purified component, the limitation of this study was the inability to determine the specific components of the plant that mediated the observed effects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com