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The sample size of this study has been calculated based on the results of a similar study [36].
The sample size of this study has been calculated based on the results of a similar study by Bornstein et al. [22].
The BEDROC metric ranges between 0 and 1 and in this study, has been calculated for α = 160.9 and α = 32.2 which corresponds to the top 1% and 5% of the relative rank accounting for 80% of the BEDROC score.
The sample size of this study has been calculated on the basis of a clinical difference of minimal relevance in terms of proportions.
The sample size for this study has been calculated on the basis of detecting improvements in this primary outcome measure following cataract surgery.
The concentration of BaP used in this study has been calculated based on previous studies on green frogs [ 16] and the environmental concentrations of BaP likely to occur in highly-polluted sites where frogs are found [ 14, 27, 37].
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The statistics in this study have been calculated using MS Excel 2010 and Python (v 2.7) with the addition of SCIPY and NUMPY [48], Pandas [49], and MATPLOTLIB [50].
In addition, the sample size for the study had been calculated based on the intervention previously implemented in Guatemala in which the population had different characteristics; as such, the study was underpowered to detect significant change in the primary clinical outcomes.
The HER for each case study has been calculated based on the long-term simulation.
The potential reduction of the environmental impacts of the case study has been calculated substituting the whole actual network by less impacting constructive solutions.
The area of the proposed study has been calculated and data for parameters like precipitation, evapotranspiration and stream flow were collected from (IMD 2014; PWD 2014).
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