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Overall, 10 of the 12 patients enrolled in this study discontinued treatment.
Only 6.3% of the patients in this study discontinued treatment because of adverse drug effects.
Despite these side effects, none of the patients in this study discontinued treatment with either of these AIs.
Two further patients in this study discontinued nilotinib due to intolerance and later progressed to blast crisis, one of whom developed a F359C mutation.
More than half of the mothers in this study discontinued breastfeeding because of their perceptions of milk inadequacy or other breastfeeding problems.
Similar(54)
In this study, discontinuing tamoxifen therapy and initiating an AI was associated with an increased rate of turnover compared to starting an AI in a patient who had never received tamoxifen.
However, no patient on this phase II study discontinued treatment due to hypertension.
55, 56 Despite this, few patients in any of the studies discontinued because of the inflammatory response.
Twelve studies met these eligibility criteria; however, one study discontinued thiazolidinediones abruptly at baseline and was not included in this analysis.
In total, 106 of the 362 T2DM patients (29.3%) entering the extension study discontinued the study prior to completion.
This study was discontinued following a planned interim analysis, having recruited 10 trainees.
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