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This specific line was chosen because it had the fewest sites with evidence of residual heterozygosity.
Because of the abnormal expression pattern observed in line 10.6, we focused further study on this specific line.
However, one BC1 line, which had higher leaf production, also led to greater reductions in biomass of the competitor grass, suggesting that this specific line may be a superior competitor.
Despite the slowly-accumulating data, a recent review [ 50] that notes the ability of HIIT to influence blood lipids has yet to be established, especially in special populations, suggesting that this specific line of research, the effects of HIIT on blood lipids, should be further examined.
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More on the specific line up problems facing Klinsmann in a minute (basically an article in itself).
(The specific line this time round, the literary straw that broke my camel's back, was: "Mold odors of atrophied testicles quilted his body in a fuzzy grey fog …" I'm not sure which disturbs me more: the horrible vision conjured up, or the annoying spelling of "mould" and "odours").
To ensure that the alterations observed in TAMR cell lines versus MCF-7/S0.5 cells were not unique to this specific cell line model, we examined whether the methylation, gene expression and pathway alterations associated with TAMR could be observed in another tamoxifen-resistant cell line model, LCC1/LCC2.
To rule out the possibility that the heterogeneous expression was due to the in vitro culture features of this specific cell line, we performed the same analysis on two other ES cell lines established in our Lab, ZjuJ1 and ZjuJ2.
In addition, the level of acetylated α-tubulin was also increased in KB-L30 cells (Figure 6D), indicating that reduced microtubule dynamic instability was present in this specific cell line.
We also cannot exclude that this specific cell line is particularly more prone to such an estrogen effect due to the fact that it is a mammary carcinoma cell line that could have multiple cellular transformations making it vulnerable to an estrogen effect.
Therefore, in this specific cell line and setting, we cannot rule out the occurrence of false-positives.
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