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To address this shortcoming, typically one of six general strategies for prolongation of half-life has been, or may be, used (Table 2):> -wrap-foot> Genetic fusion of the pharmacologically active peptide or protein to a naturally long-half-life protein or protein domain (e.g., Fc fusion [ 21 – 23 ], transferrin [Tf] fusion [ 24 ], or albumin fusion [ 25, 26 ]).
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This shortcoming can be eliminated by maintaining a small Δβ (typically <25°) for every measurement.
This shortcoming presents two problems.
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This shortcoming is not unique to Medicare.
This paper attempts to address this shortcoming.
The cloning procedure described here mitigates this shortcoming.
Tech companies are especially prone to this shortcoming.
RNA-based vectors solve this shortcoming.
Our hypothesis attempts to address this shortcoming.
However, this shortcoming is irrelevant for the hypothesis under investigation.
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