Sentence examples for this separation of function from inspiring English sources
This separation of function between fore and hind limbs was a feature of the first dinosaurs.
This separation of function allows the reconciliation of controversial reports in the literature.
This separation of function could be quantitative in nature, relating to reduced sli15-6A kinetochore levels as a result of its premature relocation to the mitotic spindle [ 5].
Moreover, this separation of function, together with our finding of very different evolutionary speeds and trajectories for spines and DoS, makes us speculate that kinases have evolved within tight constraints around spines, where maintaining spine integrity was critical to retain kinase activity.
Given this separation of functions, how can the firms be sure that every outlet under their brand cooks the food decently and cleans rooms properly?
Unlike swi3 deletion mutants, the separation-of-function mutants were not sensitive to agents that stall replication forks.
Interestingly, unlike swi3-deleted cell, the separation-of-functions mutants were proficient in the activation of the replication checkpoint, but their fork regeneration defects were more severe than those of checkpoint mutants including cds1Δ, chk1Δ and rad3Δ.
We tested these separation-of-function strains for their sensitivity to acute exposure to both HU, which causes nucleotide depletion and replication arrests, but does not directly damage DNA, and MMS, which causes alkylation damage to DNA.
The point mutants correspond to the separation-of-function mutants in S. cerevisiae (Chen et al. 2005; Minca and Kowalski 2010).
The recruitment defects and failure to maintain telomeres in vivo occur in the context of wild-type levels of activity, suggesting that the mutants described in this study are separation-of-function alleles that dissociate enzymatic activity from recruitment.
Earlier, we showed that this is a separation-of-function allele that shows a subset of DDK-associated phenotypes; dfp1-r35 cells are proficient for replication, but defective in response to alkylation damage (Dolan et al., 2010).
