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Our present study demonstrates that PL acts as an enhancer to sensitise Dox-mediated, apoptotic signalling, and this sensitisation can be obtained at subtoxic concentrations of Dox.
"This sensitisation campaign is particularly important for Niger's people, in particular for populations living in rural areas.
Furthermore, this sensitisation appears to be related to a suicidal outcome as it was found in the suicide group only.
Gene knockdown with p53 siRNA prevented this sensitisation, demonstrating that high concentrations of NO contribute to CDDP sensitivity through a p53-dependent mechanism.
5 6 29 Clinically relevant animal models of OA are essential for the identification of the mechanisms which lead to this sensitisation seen clinically.
This sensitisation value appears to have the same order of magnitude for monochromatic beam in comparison with the results quoted above with polychromatic beams.
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In this article, the sensitisation method is introduced as an approach suited to investigating nutrition-related issues affecting disadvantaged families.
In this light, the sensitisation to Fas-induced apoptosis caused by the knockdown of XIAP is easy to understand, as ligands to TNF family receptors can directly activate downstream caspases bypassing mitochondria.
However, this marked sensitisation was not observed for the siRNA/control-transfected cells.
20 In this study, sensitisation to storage mites was independently associated with allergic rhinitis.
This cutaneous sensitisation might then become systemic and subsequently give rise to other allergies, such as AR; this phenomenon is referred to as 'atopic march' and contributes to co-morbidity of allergies [ 12].
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CEO of Professional Science Editing for Scientists @ prosciediting.com