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This selectivity arises from the synthetic procedure followed to prepare the MIP.
This selectivity arises from the differential expression of thymidine phosphorylase (TYMP) which converts capecitabine to 5-FU and which has significantly higher activity in cancer cells than in normal tissue 8, 9.
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The difference between pure and mixed gas permeability selectivity arises from both solubility and diffusivity effects.
Selectivity arises from the balance of electrostatic forces and steric repulsion by excluded volume of ions and side chains of the channel protein in the highly concentrated and charged (∼30 M) selectivity filter resembling an ionic liquid.
Orientation selectivity arises from a "feed-forward" process in which the spatial alignment of the on/off center receptive fields of geniculate afferents converge onto a simple cortical cell in layer IV.
Control of the anomeric selectivity arises from conformational locking of the intermediate oxacarbenium cation.
More specifically, the change in selectivity arises from the ability of a zeolitic framework to stabilize carbenium ions, which are the intermediate species in the bimolecular cracking mechanism and the aromatic-based cycle in MTH.
The phenomenon of functional selectivity arises from the generation of discrete intracellular signaling profiles due to probe-dependent variations in the degree and/or direction of cooperativity between two GPCR binding sites (7).
The permeability barrier, and its selectivity, arises from an assembly of natively unfolded protein domains that are rich in phenylalanine glycine repeats (FG repeat domains; Denning et al (2003) and references therein) and that are grafted at a high density on to the channel walls.
In variant B7, the desired l-selectivity arises from a more favorable Michaelis Menten constant for the l-isomer compared to its d-form analogue.
Analysis of the defect tetrad signals in the homonuclear decoupled NMR spectrum indicate that iso-selectivity arises from a chain-end control mechanism (approximately a 1 1 1 ratio of sii:iis:isi; Figure S14).
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