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This segment contributes most to dimer formation.
Given that domain IV is the most significant point of departure between the otherwise very homologous IR and EGFR family of RTKs, it will be interesting to see in the future what this segment contributes to function because it is likely to serve a purpose in controlled signaling beyond that of a mere spacer.
Previous studies of TM6 by means of cysteine scanning leave little doubt that this segment contributes to the lining of the pore (5− 10), but these studies have produced conflicting results with regard to both the reactivity of specific constructs and the nature of the functional effects attributed to chemical modification.
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This segment contributed 61% of 2007 revenues [$1.4 billion].
In the example of Figure 10 the line of sight between and is partially occluded by, therefore only the segment contributes to diffusive paths.
We propose that melts from the magma reservoir at the northern end of the segment contribute around one-third of the length of this portion of the segment, whereas the mid-segment reservoir is responsible for the remaining two-thirds of the segment accretion.
We focused on the region upstream of transcription start sites (-500 to -1) since this DNA segment contributed to formation of protein complexes that regulated initiation of mRNA synthesis [ 13].
A possible explanation is that the model underlying the BLUP analysis assumes that each donor segment contributes equally to the genetic variance, i.e., the donor segment variances are homoscedastic.
Immunoreactivity studies using a truncated S-layer protein form devoid of the SLH moiety indicated that the C-terminal segment contributes significantly to S-layer immunogenicity (Ariel et al., 2002).
The new segment contributed 20% to annual earnings, thanks to steady growth in nonresidential construction.
Furthermore, even if the beefed-up segment contributed nothing whatsoever to growth, that would still leave the total companys growth rate in the range of 20%.
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