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This research effort was limited in at least three ways.
There are, however, three major uncertainties that appear to persist in the PDZ domain field, despite extensive research efforts to clarify them.
For these reasons it is necessary to intensify the research effort in order to clarify the effects of the selective elimination of senescent damaged cells in aged animal models.
This monograph describes our research effort in attacking this problem.
Still, significant further research effort in this direction is necessary.
Compared with the substantial research efforts aimed at clarifying the evolution of multiple sexual signals [ 2- 4], the cause of multiple signalling in agonistic communication has remained neglected.
It is therefore appropriate to call for more intensive, systematic research efforts directed at clarifying the causes and natural history of the condition, together with investigation of the most appropriate preventive approaches and therapeutic interventions for the condition.
Considerable research effort has been devoted to this topic.
Therefore, further research efforts are needed to clarify the mechanism of vasospasm and find new therapeutic targets.
This research begins to clarify some traits we need to adopt to become more positive in our lives.
Although most genetic and molecular alterations have been identified, characterization of all interactions between key effectors in MAPK, CDKN2A, and additional (i.e. PTEN-AKT) pathways will represent the aims of future research efforts, in order to further clarify the sequence of events inducing transformation of melanocytes and progression of melanoma.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com