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Lognormality of the distribution of this reporting ratio was assessed based on a Kolmogorov-Smirnov test (α = 0.05).
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It is unclear from this study whether this reported rate ratio was adjusted for potential confounders.
Signal detection in EudraVigilance was performed using the proportional reporting ratio (PRR) method [ 21], previously validated in this database by Alvarez et al.
These ratios are lower than the reported ratio in Firemaster 550 (4) and in Boston dust (mean 4.4; range 0.5 50).
Fig. 5 Empirical and theoretical lognormal distributions of reporting ratio.
The reporting ratio distribution was well approximated by a lognormal distribution (Fig. 5).
Furthermore, the odds ratio (OR) and the proportional reporting ratio (PRR) were calculated.
Signal detection may be accomplished by the Proportional Reporting Ratio and/or the Bayesian Confidence Propagation Neural Network.
This reported odds ratio is comparable to a 0.4- to 0.5-μg/m increased level of ECAT exposure roughly the mean levels of ECAT for the infants originally designated as exposed to moving or stop-and-go traffic.
Across 150 treatments with non-zero medication label nausea rates, reporting ratios ranged from 0 to 13.
The reporting ratios should be interpreted in their epidemiological context.
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