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It's also important to remember that this range is based on a large body of evidence using several different approaches, which all give us about the same answer.
This range is based on early clinical trials in non-HIV infected patients who had a worse outcome with doses which were unsuccessful in achieving such steady state Cmax concentrations [62 64].
This range is based on the agency's five-cycle tests using varying driving conditions and climate controls.
** This range is based on proportions found in series of cases.
This range is based on individual variability in the exercise intensity necessary to improve the aerobic fitness.
This range is based on early clinical trials in non-HIV infected patients who had a worse outcome with doses which were unsuccessful in achieving such steady state Cmax concentrations [ 62- 64].
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This range was based on the self-selected knee flexion angle observed in a previous study with similar subject demographics [ 15].
This range was based on a combination of expert feedback from the public health partners and a United Kingdom Health Protection Agency report on pilot studies that determined the relative costs of routine and targeted tests [ 35].
This range was based on the characteristics of treated diabetic patients i.e. the estimated proportion of type 2 diabetic patients by age group, the mean age of patients at the time of transition from OHA to solely insulin treatment (mean age = 66) and the minimum age at the time of this transition (age = 27).
For each such pair, the applicable day within the range is based on the number of days required for transportation outside the contiguous 48 states.
This latter dose range is based on the studies in the subgroup of atomic bomb survivors who received low doses of radiation, ranging from 5 to 150 mSv (mean dose of 40 mSv), which suggested a significant increase in the overall risk of cancer in this subgroup [ 14– 16].
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