Sentence examples for this radical mutation from inspiring English sources
This radical mutation is arguably more gruelling to watch than Kafka's descriptions are to read.
Such a radical mutation of heroism into the basest brutality is not often encountered in our daily lives, but it is a hallmark of soldiers' lives in war... Two officers are accused of the torture of Louima; 2 more are accused of beating him up.
In fact, there is an EspD-EspD protein interaction and a radical mutation in the C-terminus coiled-coil domain of EspD affects EPEC induced A/E lesion formation, EspA filament-mediated cell attachment, and EPEC induced hemolysis without affecting EspA filament biosynthesis [27].
Therefore, fairly radical mutations have to be applied in order to extinguish the biotin-binding activity of (strept avidin as previously reviewed [2].
SNPs causing radical mutations, such as premature stop codons or frame disruptions, were also identified (Additional file 10).
Of the amino acid changing mutations examined the majority were conservative mutations and the ratio of radical to conservative mutations was not significantly different for any of the variables tested due to the relatively small number of radical mutations.
Conversely, as species diverge the small number of radical mutations may be explained by the conservation of physiochemical properties, which are often conserved to maintain protein function even across evolutionary distant species [ 40].
Since the major determinant in oral cancers is the accumulation of genomic instability [ 31], and no obvious evidence was observed in radical mutations or gene expression, it is possible that the excess of somatic mutations in GTF2H5 may influence post-transcriptional regulation and correlate with tumor development.
"To have an example of how a potential single mutation could make this radical a change in pollinators in nature is exciting," says evolutionary biologist Scott Hodges of the University of California, Santa Barbara.
This radical may react with nitrogen bases of DNA and lead to mutation in nucleic acid of cancer cells and affect cell division (acts as anticancer activity) [ 39 ].
