Although the overlap between these two diseases could be coincidental, we believe that some interactions between their pathways provide biological plausibility to this proposed overlap.
Becker et al. [ 14] proposed Overlapping Cluster Generator (OCG) which decomposes a network into overlapping clusters for correct assignment of multifunctional proteins.
27 The Cochrane Collaboration has proposed overlapping categories to convey that there are no strict cut-offs for interpreting heterogeneity, and that this decision will depend on the magnitude and direction of effects, as well as the strength of evidence for heterogeneity.
It also questions the proposed overlap in roles of these enzymes in other processes relevant to atherosclerosis, including physiological arterial remodelling [25].
The proposed overlapping SGP however can be implemented in low latency systems.
Table 5 summarises some of the key proposed overlap between subgroups identified within different schemes.
However, analyses based on ROI-averaged magnitude estimates, as well as a previously proposed overlap ratio index, show that overlap in the anterior of S1 is significant at the group level, with some finger-specific anterior ROIs responding to a maximum of three adjacent fingers.
Thus, identifying a ligand binding site that overlaps with this proposed DnaK binding site would provide further validation of the location and existence of a potential DnaK binding site.
Whang et al. [2] proposed another overlapping community detection algorithm called NISE, based on seed set expansion, which starts with a seed set generated by Graclus or other methods and uses random walk to obtain overlapping communities.
The proposed implementation overlaps computation with I/O to speed up the different phases of the solver overcoming disk latencies.
