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For elimination of DNA from necrotic cells, secreted nucleases, including Dnase1 are assumed to play a central role in this process (reviewed in [11], [13]).
Although the signals inducing this autophagic attack are largely unknown, ubiquitination of cytoplasmic bacteria and the binding of the autophagy adaptor protein p62/SQSTM1 play a role in this process (reviewed in [49]).
Although numerous aspects of the immune system are responsible for slowing the growth of Mtb, the antimicrobial molecule nitric oxide (NO) appears to be essential for this process (reviewed in [2]).
Notch activity is a major player in this process (reviewed in [11], [21], [41]) and the parallel between embryonic neurogenesis and in vitro neural differentiation of ES cells is reinforced by the similar dependence on Notch signalling to maintain a population of NPs engaged on neuronal production.
Maintenance of proper gene expression in differentiated cells is essential for the development of multicellular organisms and epigenetic regulation is an important player in this process Reviewed in: [ 1- 3].
The retroviral lifecycle depends on insertion of viral DNA into a host cell chromosome, and integrase (IN) is the enzyme that orchestrates the key catalytic events involved in this process (reviewed in Craigie, 2002; Lewinski and Bushman, 2005).
Similar(49)
This is discussed in relation to experimental observations and the evidence for this process is reviewed.
Therefore, solid state fermentation and their effect on the formation of value-added products by this process are reviewed and discussed.
The list of uncertainties generated by this process was reviewed at a meeting of the Steering Group to decide which to take forward to the ranking stage.
Publications collected by this process are reviewed and classified by two or more coders according to the schema in Table 1.
"Now, we will meet with community stakeholders as we have done all the way along this process to review options going forwards.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com