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This principle is supported by the seminal finding that sensitizing epidermal growth factor receptor (EGFR) mutations are present in about 17%% of lung cancers and are targetable with the FDA approved EGFR tyrosine kinase inhibitors (TKIs) (erlotinib, gefitinib and afatinib) [2, 3].
This principle is supported by the United Nations Convention of the Rights of the Child.
This principle is supported by the excellent outcome of liver transplantation in patients affected by some forms of amyloidosis.
This principle is supported by psychometric studies demonstrating that health status and QOL are related but distinct constructs [ 41, 42] – health status alone does not capture all of QOL.
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Third, a small palette principle is supported such that the total number of colors used in the average design was smaller than would be expected under statistical independence.
The first exposure principle is supported by theories of causal inference that hold that causality can only be assessed by either a randomized trial or an observational study that closely mimics a randomized trial.
There can be no doubt that new legislation is needed and should, in principle, be supported, but that does not make the current bill fit for purpose.
However, many methods, for example those which utilize PCR to create small amplicons are not constrained by a requirement for large template molecules and can in principle be supported using DNA amplified from sorted chromosomes.
Acting in the child's best interests involves the combined principles of beneficence and non-maleficence [ 93], and these principles are supported by local RECs' essential role in filtering out research protocols with an unacceptable risk: benefit profile so that parents are only asked to consider participation in appropriately vetted, safe studies (the Nuffield "fair offer" concept) [ 97, 98].
The weaker of the large cardinal principles are supported by intrinsic evidence (see section 3.1).
Currently all our provinces have either adopted or adapted the PRONADIA principles, being supported with their own budget (federal health care system).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com