Sentence examples for this primary event from inspiring English sources

Finally, microRNAs might silence gene expression by a common and unique mechanism; and the multiple modes of action represent secondary effects of this primary event [ 1- 3].

As evidence supporting miRNA functioning in vasculopathy of SSc accumulates, we hypothesize that this primary event in SSc pathogenesis is controlled by a complex miRNA network.

We can visualize this as a small bubble without perturbing overall backbone conformation, but this primary event is crucial to helicase activity and subsequent assembly of the cellular DNA replication machinery.

Although α-synuclein deposition consistently occurs in various neurodegenerative diseases it is still unclear whether this is the primary event driving disease pathogenesis or is just an epiphenomenon [ 38 ▪].

This suggests that the primary event in the sequence leading to chronic inflammation in AT is metabolic dysfunction in adipocytes, followed by production of immunological mediators by these adipocytes, which is then exacerbated by activated ATM, activation and recruitment of immune cells.

This study concluded that disk degeneration was the primary event leading to degenerative spondylosis.

This has likely been because a decreased effective circulatory volume is considered the primary event in the development of CIN, in patients with CHF [ 20, 21].

This finding provides a very strong evidence that early progressive renal decline is the primary event in the development of diabetic nephropathy.

In head trauma, for example, the blow to the head is the primary event.

"You feel these weekly events in the zeitgeist and the live show, again, is the primary event.

However, what may be of greater concern is the secondary inflammatory response that will result from the primary event.