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The meaning of this preferential location is not known, but some hypotheses are considered and the observed trends are discussed.
The reason to this preferential location is unknown and one factor could be expression of chemo-attractants, such as S100A9.
This preferential location close to genes was also found for other MITE families in Brachypodium, sorghum, and maize (Han et al. 2013).
This preferential location of IESs corresponds to the region of the transcript where in other eukaryotes NMD most efficiently identifies aberrant mRNA transcripts (van Hoof and Green 1996; Silva et al. 2006; Longman et al. 2007) and more rapidly promotes termination of protein synthesis.
Similar(56)
Since the main BaP and other xenobiotic biotransformation reactions take place in the liver, this is also the preferential location for collateral toxic events [ 26].
This pattern suggests that the preferential location for fusion is on a limited membrane domain at the sub-apical flanks and not at the extreme apex (additional file 2), in agreement with the recent hypothesis of an annulus shaped release zone [ 11, 12].
Transmission electron microscopy studies indicated that this behaviour was due to the preferential location of silicates in the PBS phase than in the PLA phase.
This is borne out by the preferential location of metastatic cells in the highly vascular paracortex rather than in the follicles 10.
Data from this study supports the latter notion, and further refines the preferential location of SC in the LEC.
Then, we compared the number of predicted repressors located on chromosome 19 with the number of predicted repressors located elsewhere (see Table 2 and section 'Inference of the preferential location of zinc-finger repressors of ERVs on chromosome 19 using Fisher's exact test with a noisy classifie r' in Supplementary Information).
Both thermodynamic and kinetic theoretical analysis predicated the preferential location of RGO in the TPU rather than PP phase.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com