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Possible reasons for this poor agreement include (a) a true lack of north south conjugacy between measurement sites, (b) an invalid comparison between global (SuperDARN radar) and local (MINIS balloon) measurements and/or (c) radar absorption resulting from precipitation-induced D-region ionosphere density enhancements.
Unfortunately, some of this poor agreement might be due to temporal changes in the Black Sea, because the datasets being compared were not obtained contemporaneously.
As the sizes of the small tumours are less than three times the full-width-at-half-maximum, the influence of partial volume effects may be relatively high, causing this poor agreement with pathology.
This poor agreement reflected an accumulation of disagreements about the quality of evidence and importance of the individual outcomes that were considered for each question.
This poor agreement of measured and calculated osmolality during mannitol infusion might be due to the osmolal gap, which is the difference between the two values.
As already mentioned, this poor agreement level is mostly due to different representations of the data that cannot be readily inter-converted (Supplementary Discussions S1 and S3).
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For this item, the poor agreement was most likely due to the rather unstable behaviour caused by the school schedule which influenced the students' use of the computer on school days.
The Bland-Altman plot demonstrates the poor agreement between FAF and GVF.
Again, this demonstrated poor agreement between the two guidelines (kappa coefficient 0.13, p = 0.005).
This demonstrates poor agreement between the two guidelines with the kappa coefficient on day 1 of 0.26 (p = 0.004) and 0.07 on day 3 (p = 0.34).
The lack of reproducibility associated with this issue and poor agreement between different commercially available EGFR antibodies (Anagnostou et al, 2010) have resulted in confusing literature on assessment of the impact of EGFR testing and lack of its adoption as a companion diagnostic test.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com