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Outside the brain, this pathway involves hormones and growth factors, important in normal development.
This pathway involves reduction of sulfate; the most abundant sulfur source in grape must, into sulfide through the sulfate assimilation pathway and incorporation of sulfide into an amino acid precursor.
These activities are consistent with a role in mycolic acid biosynthesis as this pathway involves multiple ester and thioester bonds.
This pathway involves the inactivation of the GTPase activating protein TSC1/2 by Protein Kinase B (PKB/Akt -mediated PKB/Akt -mediated17]–[19].
This pathway involves cell surface receptors (Notch, insulin, Tie2) and subsequent up-regulation of the transcription factor Hes3 [23], [24], [25], [25].
This pathway involves the regulation of the activation state of cofilin through phosphorylation mediated either by PI3K-RHO-CDC42-PAK-LIMK or PLC-LIMK [25].
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A small Massachusetts biotech company, Proteostasis, is investigating this pathway involving IGF as a potential target for anti-ageing drugs.
Furthermore, the dysfunction of this pathway involved in cancer development is obvious, and targeting the pathway as a therapeutic strategy has been extensively explored, but the efficacy of the targeted therapies is still under development.
This observation suggests the importance of this pathway involved in the pathology of prostate cancer.
This pathway involved 55 up-regulated genes and 24 down-expressed genes.
A different stress signal such as glucose starvation rapidly activates this pathway involving p53 and AMPK.
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CEO of Professional Science Editing for Scientists @ prosciediting.com