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This pathway constitutes a molecular switch that enhances immune and pro-inflammatory gene expression in T cells undergoing adhesion at sites of activation and effector function.
This pathway constitutes a novel pathway of host-pathogen interactions and serves to balance immune reactions.
Overall those data support the idea that the regulation of IIRc pathway by KL is conserved between C. elegans and mammals and that this pathway constitutes a relevant target for lifespan control by KL in mice.
As the inhibition of cholesterol biosynthesis has been shown to reduce significantly tumour cell growth, this pathway constitutes a highly promising target for anticancer drug design (Rao et al, 1995).
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The other five enzymes in this pathway constitute two different enzyme complexes located in the cytoplasm.
This part of the pathway constitutes one of the first biological processes to have been defined at the gene level, described in some reviews as early as the 1980s 22 244).
By accounting for these various influxes and effluxes, the pathway constitutes an open system that operates at a dynamic steady state, with small amounts of material continuously flowing in and out of the system.
This miR-31/LATS2/PPP2R2A pathway constitutes a new growth regulator in lung cancer.
We propose that this integrin-FAK pathway constitutes a sensitive neuroglial sensor for regulating neurotrophic support or neuronal function in the CNS.
Further, we demonstrate that IRF5 is activated by Dectin-1 signaling in these immune cells and that this Dectin-1-IRF5 pathway constitutes a critical limb for their orchestration of NK cells.
The row corresponding to p38 MAPK signaling pathway constitutes a good example for this scenario.
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CEO of Professional Science Editing for Scientists @ prosciediting.com