Sentence examples for this pathway comprised from inspiring English sources

The activation of this pathway, comprised by Ras, Raf, MEK1/2 and extracellular signal-regulated kinase (ERK 1/2, leads to tumour development and progression through the activation of transcription factors that stimulate cell proliferation and metastasis (Dhillon et al, 2007; Katz et al, 2007).

This pathway comprises, amongst others, three reverse steps of β-oxidation, catalyzed by three separate enzymes: β-ketothiolase, 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase reactions.

In essence, this pathway comprises the enzymes under study: GFAE, ADH3 and SFGTH.

15 This pathway comprises a physically and functionally distinct sub-compartment of the brain circulation.

This pathway comprises cellobiose phosphorylase (CBP), which cleaves intracellular cellobiose into glucose and glucose-1-phosphate (G1P) [ 12].

This pathway comprises part of Arginine and Proline metabolism [ 34] with all the reactions between AcCoA and Ac catalyzed by highly-expressed enzymes i.e. all reactions included in H.

This pathway comprises genes responsible for signaling events downstream of the CD28 superfamily of receptors that are required for the activation of T lymphocytes (in conjunction with the T cell receptor complex).

This pathway comprises of two reactions UDP -d-glucuronate synthesis from UDP -d-glucose, and the synthesis of UDP -d-xylose from UDP -d-glucuronate, whicatalyzedtalyzed by UDP -d-glucose 6-dehydrogenand and UDP -d-xylose synthase enzymes, respectively.

Finally, the pathway comprised 30 nodes and 38 edges (Fig. 1).

However, the pathway comprises a multitude of signaling molecules and displays complex interactions.

In this review, the role of a signal transduction pathway comprised of the lipid kinase, phosphatidylinositol 3-kinase (PI3K), and the serine/threonine kinase, Akt (or PKB), in chemotherapeutic resistance will be explored.