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However, if the target gene expression was only examined at this one time point, the alteration of mRNA expression induced by xanthone compounds may be underestimated.
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Although we agree that having single cell data would have been ideal, obtaining a sufficient data set for the analysis of tamoxifen inducible changes in this rare neuronal population was not feasible in the set of experiments presented (note that the data on OFF cone bipolar cells in Arman and Sampath (2012) required nearly 1.5 years to collect, and this is for one time point).
On day 29, two-way ANOVA revealed an effect of estrous (P < 0.05; Table 3) and an estrous-by-treatment interaction (P < 0.01; Table 3; Figure 5E); however, we caution against over-interpretation of this result since this occurred at just one time point, and AUC transformation yielded no effect of estrous over multiple testing days.
Although preventive behaviors are dynamic, this analysis is based on assessment at one time point.
Moreover, this study examined only one time point and not changes in approaches over time.
This extends previous evidence which is mainly based on economic difficulties at one time point.
An important limitation of this study is that only one time point was studied.
The literature on reports of interpersonal discrimination over time is limited, as there are few datasets with this information at more than one time point.
Only one patient had evidence of in vitro neutralising antibodies against uricase activity; this was measurable at only one time point.
The courses of arterial lactate and pH are shown in Figure 4A and 4B, respectively, showing optimum pH levels in normal-weight patients and a trend towards higher lactate levels in patients with BMI ≥ 30, although this is only significant at one time point.
Kinetic solubility values are approximate values usually based on one measurement at one time point.
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