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Exact(17)
This nucleotide is used to transfer chemical energy between different chemical reactions.
The interspecies conservation of this nucleotide is high and this mutation has been predicted to be pathogenic [15].
In addition, this nucleotide is a 'hub' molecule in several metabolic routes, including phospholipid metabolism.
Because this nucleotide is not conserved in the murine Fancd2 gene, however, the functional significance of these changes remains unclear.
Several studies indicate this nucleotide is important in decoding genetic information, particularly at the step of initiation [ 21, 22, 52].
This nucleotide is not conserved in the murine Bach1/ Brip1 gene, however, so may not, therefore, be functionally significant.
Similar(43)
This nucleotide was synthesized by a procedure that included protection of the cytosine amino group by di n-butyl)formamidi n-butyltion, formamidine incorporation into DNA.
This nucleotide was identical to the border nucleotide of the 2.6-kb WFP candidate region (Miura et al. 2010), indicating that the SNP can be an FNP of the OsSPL14-ST12 allele.
If both genomes exhibited the same nucleotide as one another and as one of the two human alleles, we inferred that this nucleotide was the ancestral state.
However, this nucleotide was not present in the single trace file of the Canis familiaris Trace Archive [ 34] covering this sequence.
The T H1′→X H2 NOE (the imidazole proton of 1, N-ϵdG; note the modified numbering scheme for this nucleotide) was missing, interrupting the NOE connectivity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com