In this model, repeated UVB exposures generate cyclobutane pyrimidine dimers in DNA rather than double strand breaks [7].
Fourfold cross-validation results for this model (repeated 10 times) are reported in Supplementary file 3, showing consistency in terms of coefficient and prediction accuracy.
In this model, repeated application of bleomycin, an anti-tumor antibiotic originally isolated from the fungus Streptomyces verticillus [ 19], is used to induce inflammation and subsequent fibrosis in skin [ 20].
Dismantle and clean the model, repeat the procedures (1)–(2) to refill the model. 5.
Page 6 "select the model "repeated.
Friday: 8, "Everybody Hates Chris"; 8 30, "The Game"; 9, "Top Model" repeats.
The model repeats the calculations for all the time steps of the history by solving Eqs.
Under this model, single-repeat mutations have a probability of p whereas multirepeat mutations (length of change ≥1 repeat) have a probability of 1 − p. For multirepeat mutations, the distribution of step size, | i − j|, is given by a truncated geometric distribution γ g, i, j).
First, to further confirm tear secretion is chronically reduced in this model, we repeated treatments corresponding to the work-rest-sleep cycle of office workers on a daily basis up to 20 days (Figure 1B).
Post-hoc, this model was repeated for patients with clinically relevant (> 30 mm) baseline pain only.
