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In the future employers may be more involved in course design and development, although this model remains to be tested.
Although the link between increased glutathione levels and decreased α-synuclein toxicity in this model remains to be established, it is plausible that increased antioxidant activities associated with the established role of glutathione in protection against oxidative stress [50] affect α-synuclein aggregation.
This model remains to be fully evaluated.
The role of increased circulating levels of ghrelin in this model remains to be elucidated.
This model remains to be tested in more detail in future studies.
In particular, whether autophagy is a survival or a death mechanism in this model remains to be established.
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Important work related to the model remains to be done.
Whether sex hormones, IL-28B polymorphism, and natural killer p46 expression, as suggested in the gender differences in humans, play a role in this mouse model remains to be investigated.
The general validity of this particular charge-driven interaction model remains to be demonstrated for other structurally diverse amyloidogenic proteins.
The durability of the verein model remains to be seen.
How that fits in with the Eckenhoff model remains to be seen.
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