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The choice of this mixed function was empirical and for simplicity in the mathematical simulation, as it is appreciated that other complex peak shapes are also considered for cellulose.
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CYP are the mixed function oxidase enzyme family (EC 1.14.14.1: mono-oxygenases that contain iron-dependent protohaematin IX).
The fatigue life data were statistically analyzed and a mixed probability distribution function of two lognormal distribution functions was proposed in the present paper, and results showed that the mixed function is suitable to describe the fatigue life distribution of aluminum alloy LC4CS in the VHCF region.
Inhalation anesthetics are metabolized in animals and humans by the mixed function oxidases of liver microsomes.
These observations suggest that inhibition of the mixed function oxidase system using triazoles could increase systemic 4-HPR levels.
Hydrogen peroxide and superoxide are produced during metabolic activation of PCM in the mixed function oxidase system [ 47].
The toxicity of these compounds was decreased by adding the mixed function oxidase system (MFOS) inhibitor, SKF-525A (25 microM) to the cultures.
Highly reactive free radical metabolites are also formed by the mixed function oxidase system in hepatocytes via CYP2E1, causing severe centrilobular necrosis [ 5, 6].
Cutaneous NADPH-CYP reductase (determined as NADPH cytochrome c reductase), a component of the mixed function mono-oxygenase system, significantly decreased with age (in contrast to the liver where it remained constant).
The findings support the hypothesis that vinyl chloride is hepatotoxic because it is converted into a toxic metabolite by components of the mixed function oxidase system of liver endoplasmic reticulum.
It was also proposed, that the varying effects of CIM on P450 enzymes could be attributed to different CIM binding affinities for these mixed function oxidases (Faux and Combes, 1993).
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