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Further improvement should focus on maximizing Ab function, which takes into account both titer and avidity, and this may require improved conjugate design in addition to adjuvants.
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Further improvement in survival may require improved strategies to deal with this problem.
Prevention of the related subsequent injuries may require improved injury recovery and rehabilitation processes and there is a clear role for sports medicine professionals in this.
This may require actions to improve the uniformity of the urgency assignment.
The future application of targeted immunotherapy may thereby require improved individualized immunodiagnostic selection of patients based on their relative expression of Ep-ICD versus EpEx in the tumors of each affected patient.
The pathways models may also require improved parametrization, as they are not at present structured adequately to lend themselves to validation.
This may require practice.
False positive results suggest that a model established by NIRS may be flawed and requires improving by enlarging the sample size and sampling region or changing the wavelength region.
Preliminary qPCR measurements suggest knockdown of Smed-mll5-1 mRNA is incomplete (data not shown) and that analysis of this gene may require longer feeding schemes or improving the design of our RNAi constructs.
This goal may require a combination of biomedical interventions (improving diagnostic capacity, implementing active case detection strategies) and structural interventions (reducing crowding, improving ventilation and prison conditions) to achieve a substantial impact on the extraordinary burden of TB in Brazilian prisons [ 23].
However, this approach may require additional data quality checks to improve accuracy and precision of the spatial data captured by citizens.
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