Chronic and progressive course is typical of disseminated histoplasmosis in non-immunocompromised adults of middle age or older, and this clinical manifestation represents 1% of all symptomatic cases.
The ultrastructural manifestation represents a "gold standard" method to identify autophagic vacuoles [ 43].
Early clinical manifestation represents only 10% of the cases, but the prevalence of pre-clinic atherosclerotic manifestation in young adults is much higher [3], [4].
The clinical disease manifestation represents end-stage insulitis, since only 10 20% of the insulin-producing β-cells have been estimated to still be functioning at the time of diagnosis (2).
Sarcoidosis is an idiopathic inflammatory disorder involving multiple organs, and ocular manifestation (represented by granulomatous uveitis) is one of the common features.
The possibilities of manifestation represented by plants and animals are relatively limited; external appearance reveals their secrets to observers, and no one confuses a cabbage with a carrot, or a horse with a donkey.
Given this level of possible hybridization, we suggest that treating New World Pteridium as three species the diploids P. esculentum and P. aquilinum, and hybrid P. caudatum (in all its manifestations)—represents best the biological situation in the genus (Thomson and Alonso-Amelot 2002; Zhou et al. 2014).
Inflammation is typically self-limiting in time and relapsing episodes of clinical manifestations represent a hallmark of Behçet's disease.
Its causes are protean but its manifestations represent dysfunction of specific neurohormonal pathways of the central nervous system.
Somatoform dissociation is a specific form of dissociation with somatic manifestations represented in the form of 'pseudoneurological' symptoms due to disturbances or alterations of normal integrated functions of consciousness, memory or identity mainly related to trauma and other psychological stressors.
