This approximation makes substantial simplification possible, for instance in the case of a batch reactor, it allows a naturally sixth order system to be approximated by a two dimensional manifold for the dynamics of two modified Thiele moduli.
All authors credited with this work made substantial intellectual contribution to the submitted manuscript.
All the authors of this manuscript made substantial contributions to the conception and design, acquisition of data, and analysis and interpretation of data.
TW was the principal investigator on this study, made substantial contributions to the conception and design of the study, enrolled patients, participated in data acquisition, analysis, interpretation, and presentation.
LAA was the principal investigator on this study, made substantial contributions to the conception and design of the study, enrolled patients, participated in data acquisition, analysis, interpretation, and presentation.
The key input parameter affecting the cost effectiveness was the relative risk of death from breast cancer; small differences in this parameter made substantial differences to the cost effectiveness.
SBW was the principal investigator on this study, made substantial contributions to the conception and design of the study, enrolled patients, participated in data acquisition, analysis, interpretation, and presentation.
HJS served as senior author on this manuscript and made substantial intellectual contributions to this study.
It would be possible for this team to make substantial gains simply by protecting Newton better.
I hope this Parliament can make substantial progress going forward, he concludes.
