This ring is the major target for transcatheter aortic valve prosthesis sizing.
Most breast cancers overexpress oestrogen receptor-α (ER-α), and this molecule is the major target of the anti-estrogens, such as tamoxifen, used to treat the disease.
To test if this is also the major target of lamprey VLRBs, we used a panel of PR8 viruses with 3, 6, 9, or 12 amino acid substitutions located among the five defined antigenic sites (Das et al., 2013).
Corresponding to this increase of miR-34a, plasma expression of SIRT1, the major target of this microRNA, shows a precipitous reciprocal decrease starting at 4 months of age, while PBMCs exhibit a gradual decrease in SIRT1 from this age onward.
Active suppression of the acoustic transmission through plate structure is the major target of this paper.
This structural protein represents the major target of cellular immune response during HCMV infection [20], [21], and also in vitro HCMV-infected cells are recognized by 70 90% of cytotoxic T lymphocytes (CTLs) [22].
We recently showed that deiminated fibrin is the major target of this family of autoantibodies in rheumatoid synovial tissue.
PSII is generally considered as the major target of this phenomenon (photoinhibition) as it is less stable than PSI under strong light treatments [ 5, 6].
This was in agreement with the finding in both patients that viral antigen was detectable by immunohistochemical analysis only in alveolar epithelial cells of the lungs, which indicated that this cell type is the major target cell in humans.
Given the importance attributed to insulin resistance in the cardiometabolic syndrome, this defect has been the major target for therapy and, consequently, various types of drugs considered to alleviate insulin resistance have been tested.
