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The phrase "this large initiative" is correct and usable in written English.
You can use it when referring to a significant project or program that is currently being undertaken or planned. Example: "This large initiative aims to improve community health and well-being through various outreach programs."
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The purpose of this large initiative is to increase the knowledgeregarding the identification of disease markers, potential targets of therapy, aswell as the insight into variations of expression observed during development,health, and disease (http://www.HUPO.org).
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This is the largest initiative so far in promoting this energy source in the developing world and we are confident that it will bring benefits to millions of people.
This study represents a large initiative to establish a network of ICUs in Peru and understand selected aspects of clinical management and patient-centred outcomes of mechanically ventilated patients.
Indicated by the announcement of Prof. Junji Kido from Yamagata University in 1st Plastic Electronics Asia (Millennium Seoul Hilton Hotel, June 24 26, Seoul Korea) announcing an OLED lighting panel factory, this was by far the largest initiative in East Asia in the field of OLED lighting.
Taken together, these findings and the processes described here are the first of their kind relative to this large research initiative and provide valuable insights into the nature and functioning of the HIV/AIDS clinical research networks.
How do they connect back to the larger initiative?
The bridge between East and West also drives the creation of the Institute's Philosophy and Culture Center, the larger initiative that includes the philosophy prize.
During the 2009 World Economic Forum they launched the largest initiative to develop sustainable, healthy and affordable classrooms in the US and abroad.
And secondly, there is a large initiative in place in the UK, mandating programming education in public schools.
EHR adoption will require significant efforts with regard to workforce since it is a complex and large initiative in healthcare industry.
The UK has a large initiative focused on improving the timeliness of cancer diagnosis.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com