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Using gene expression profiling, additional studies from this laboratory demonstrate that MSCs express bFGF, FGF-7, IL-1, IL-6, PIGF, transforming growth factor-beta (TGF-β), TNF-α, and VEGF, which was augmented in response to hypoxia.
Several observations, including studies from this laboratory, demonstrate that asbestos generates free radicals in the biological system that may play a role in the manifestation of asbestos-related cytotoxicity and carcinogenicity.
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Earlier work from this laboratory demonstrated a bumetanide-inhibitable K+ uptake activity in cultured bovine lens epithelial cells, but not at the anterior surfaces of intact bovine lenses isolated in an Ussing-type chamber.
Additionally, previous studies in this laboratory demonstrated that total cellular pools of ubiquitin were not altered by Ni ions [21].
Earlier in vitro work from this laboratory demonstrated that P2Y1R-enhanced astrocyte and neuronal protection was dependent on astrocyte mitochondrial ATP production [22].
Previous studies from this laboratory demonstrated specific, high efficiency targeting of panitumumab in HER1-positive tumors in multiple xenograft models.
This laboratory demonstrates excellent accuracy in international trace elements external quality assessment schemes and is one of the participants of the United Kingdom TEQAS.
Previous work in this laboratory demonstrated that non-invasive T2-weighted MRI can reliably detect small in situ cancers and distinguish between in situ and invasive cancers [ 2].
Previous work from this laboratory demonstrated that magnetic resonance imaging (MRI) detects early murine mammary cancers and reliably differentiates between in situ and invasive cancer.
Previous work in this laboratory demonstrated that MIN lesions and invasive cancers can be identified and distinguished by MRI based on the signal intensity, size and shape [ 3].
Previous research within this laboratory demonstrated that polysomy of chromosomes 9, 7 and 17 are associated with recurrence (Bartlett et al, 1998, Watters et al, 2000), but that these genetic events are not linked with polyploidy (Bartlett et al, 1999).
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