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These results further support that hMEPE/OF45 functions through the CHK1 pathway to affect cell response to DNA damage, because this kind of checkpoint response, G2-phase cell accumulation, is ATM independent (Xu et al, 2002) but CHK1 dependent (Wang et al, 2003).
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I've always known I wanted to have kids, though I suppose it can be tough to know whether that was a true desire or the kind of checkpoint-based "maturity" and conformity Tyler Durden was so angry about (it's just what you do).
Fifteen minutes away from Benghazi, we ran into another kind of checkpoint.
In addition, a second kind of checkpoint, here termed the mitotic spindle checkpoint, is activated during every cell cycle and only silenced once all chromosomes are properly attached to a bipolar spindle and ensures accurate chromosome segregation and protects against aneuploidy.
Since the length of time between initiation and the arrival of the middle coat is the most variable of all the endocytic stages, it seems likely to involve some kind of checkpoint.
The security required for this kind of applications is similar to the one of the previous step, and it is possible to set checkpoints in the computation in order to prevent the complete loss of data in case of failure.
Extension of this kind of analysis to human cells derived from XP patients confirmed that lack of NER-dependent processing prevented UV-induced checkpoint activity in non cycling fibroblasts, revealing that XP cells are not only deficient in repairing UV lesions, but they are also deficient in the G1 and G2/M UV-induced checkpoint [56,57].
This kind of challenged me.
This kind of speed kills.
This kind of criticism hurts.
"This school attracts this kind of kid.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com