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That is, probes of variable sequence all designed against the same gene can have different affinities for the target sequence, bringing into question the number of probes required for each target and how this issue changes as a function of probe length and characteristics of the target organism's genome.
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If so, how might this issue change the plot of the show?
Unless the three P's of society -- the politicians, police and the public -- do not prioritize the dealing of this issue, change age-old patriarchal mindsets and prepare to walk the talk, we will continue to witness such atrocities and teach our little girls some bitter lesson.
At this stage, the issue changes from a descriptive to a prescriptive or normative one.
Through this lens, the issue changes from figuring out how to crush scary bad guys, to figuring out how to protect vulnerable kids.
We need a three-pronged approach to address this issue: policy changes; industry self-regulation; and more parental tools, monitoring and education.
To address this issue, the changes in the HMGB1 level were examined.
Even though we used Kosambi's map function to convert observed recombination values to map distances, any such analysis still suffers from this issue, and changes in the real recombination rate in larger intervals are likely to remain undetected.
"There is a sense that the times have changed and that the logic of this issue has changed," a Democratic pollster told the Post.
This issue of change is important to him.
This issue has changed during the last decade in its degree of importance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com