Sentence examples for this is most problematic from inspiring English sources
This is most problematic for the Pat1 mutant strain, as pat1Δ is known to affect stress granule and P-body formation to some extent [8], [32].
This is most problematic for the K2 K3 gap in the eastern Balkans, for which we have no observations of A. transcaspicus.
This is most problematic in the case of large clones and leads to an underestimation of the clone size.
This is most problematic for the infected patient, because quasispecies variation confers remarkable adaptive potential on HCV and has been implicated in the evasion and control of the host response to infection and in differential sensitivity to IFN therapy.
This was most problematic in Schubert's Arpeggione Sonata in A minor, since Classical sonatas tend to place the pianist in a supporting role.
This degradation is most problematic for samples containing only small quantities of cellular material, for example, touch DNA samples.
In clinical serodiagnosis detecting IgM, this cross-reactivity is most problematic with secondary infections due to the difficulty of differentiating antibodies elicited by primary infections from those elicited in a secondary infection [27], [28], [29].
But for Mr. Wheeldon, more than any other eminent choreographer today, the pas de deux is central and crucial — and yet this is where his work is most problematic.
But it is on this subject that the disjointed style is most problematic.
In this study, non-daily consumption of breakfast was greater among higher SES (Private school) students, for whom obesity is most problematic in this context [ 6, 51].
