Sentence examples for this is especially challenging when from inspiring English sources

This is especially challenging when targeting interactions with ubiquitous recognition modules for example, PDZ domains, which bind C-terminal sequences of partner proteins.

This is especially challenging when trying to create affordable and accessible communities for families of all economic levels.

This is especially challenging when complexes of several proteins are considered.

This was especially challenging when new concepts and ideas were introduced.

This was especially challenging when trying to differentiate their role as a content expert.

This problem is especially challenging when parsing multi-dimensional genomic data.

This type of sub-volume averaging is especially challenging when multiple species are present.

Nevertheless, this underlines the importance of true informed consent, which is especially challenging when approaching minors and their guardians.

"Which," he added after a pause, "is especially challenging when you have a lot of it coming every second".

Furthermore, so-called escape peaks, scatter peaks, peaks originating from the instrument as well as overlapping peaks can complicate interpretation, which is especially challenging when investigating non-homogeneous multilayer materials such as paintings.

The first "would be a steep hill to climb under any circumstances," but is especially challenging when money is in short supply - and Bok offers no feasible solutions.