Sentence examples for this is a substantial issue from inspiring English sources

This is a substantial issue requiring attention.

Since literally every individual in his or her life is likely to somehow depend upon medical care, the challenge of cultural diversity and intercultural understanding in this context is a substantial issue when talking about international stability at the individual and societal level.

While no one keeps state-by-state numbers on parole backlogs, Mr. Mauer said, "nobody here is aware of that being a substantial issue in other states".

But for many people, the core of the immigration question – and one which I fully accept is a substantial issue – is immigration from non-European countries especially when from different cultures in which assimilation and potential security threats can be an issue.

Dale Ho, director of the ACLU's voting rights project, questioned Hans von Spakovsky, a former Justice Department official and member of the Presidential Advisory Commission on Election Integrity, who is one of the most prominent people arguing that noncitizen voter registration is a substantial issue.

When assessing imported malaria cases, underreporting is a substantial issue.

Illicit drug use for recreational purposes is a substantial issue within Western society and causes significant health issues.

Since there have been growing numbers of non-inferiority trials published in recent years, this may be a substantial issue.

For that reason, it says, the court should interpret the statute as it did in the Zadvydas case, to avoid what would otherwise be a substantial issue of due process.

"But there's a substantial issue about my client's mental state".

The assessment of comparable dosimetry for animals in different life stages has been a substantial issue in discussions of the analysis of these data.