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This is a central problem in most medical treatment: patients are known and treated as totally separate from the families in which they live.
Of course, this is a central problem in visual perception more generally.
No membrane physiologist could ignore the extremely deleterious effects of changes in ion concentrations and gradients of the magnitude that would occur with internalization, or fail to realize that this is a central problem that hypotheses of the origin of eukaryotes must resolve.
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This was a central problem for Hobbes, who went to great trouble to prove that, in all our acts, our real aim is always our own interest.
Understanding the factors underlying this enormous variability is a central problem in evolutionary biology.
Corrosion is a central problem in shipping and is addressed in this chapter.
Graphical model processing is a central problem in artificial intelligence.
Sensor localization is a central problem for sensor networks.
Protein folding is a central problem in biological physics.
The definition of concepts is a central problem in commonsense reasoning.
Integrating actions and state constraints is a central problem in knowledge representation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com