"You have to be people of means, because this involves a lot of expense," says Luz Flores, explaining how mayordomos are selected.
While there are clearly real strengths in a study design where pre-pregnancy data are available, this involves the expense of retrieving information from large numbers of women who do not have a pregnancy in the timescale of the study.
In addition, the HDS enzyme (4-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase) flavodoxin reductase and NADPH dependent metalloprotein, (Rohdich et al. 2003; Seemann et al. 2006) involve an extra expense of reducing power to carry out their catalytic functions (Hunter 2007).
This phase of the project is characterised by a high level of uncertainty and it involves a huge expense in the preparation of the proposal and important mobilization of resources.
The use of multiple restriction enzymes for TMDH has theoretical advantages, but increases the expense of the method since it involves an additional set of microarrays.
Some also may not have fully considered the costs of operating as an intermediary, which involves a lot of compliance-related expenses.
Whether death comes at 35 or at 100, it will probably involve a lot of expense in the last year of life.
The MoJ has said the reforms will encourage people to take advantage of alternative routes to resolution – such as mediation – which will not involve the expense of court proceedings.
Trevor Guthmiller, executive director of the American Coalition for Ethanol, says the tax break was deserved because ethanol did not entail the cleanup costs of gasoline pollution and did not involve the expense of maintaining the military capacity abroad to ensure steady supplies of imported petroleum.
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Many organizations avoid migration of systems like this because they involve a large sum of upfront capital expense.
