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Here, we report that Itch strongly interacts with LITAF, and that this interaction relies on the WW domains of Itch and on the two PPXY motifs found in the N-terminus of LITAF.
Our studies clearly indicated that both p53R175H and p53R273H are able to directly bind DNA-PK and that this interaction relies on stathmin expression, a finding also proved in primary HG-EOC tumours (Fig 8).
This interaction relies on the integrity of a positively charged amino acid cluster located in the first sheet of the CXCL12 β strand, which forms the canonical binding motif for HSPG.
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In the B. burgdorferi case, the interaction relies on a dimer built by two identical monomers, whereas in D. melanogaster Pur-α, an intra-molecular dimer is formed by its PUR repeats I and II.
This protein-protein interaction relies on molecular recognition via a small set of residues in each protein.
The Raman and FTIR analyses indicate the DMF-FePc interaction relies on coordination bonds between N atom (from DMF) and Fe atom (from FePc).
In general, plant microbe interaction relies upon mutual benefits, whereas plants provide oxygen and organic carbon to the microbes in return microbes provide minerals and metabolites required by plants for their growth.
The realization of the strong coupling interaction relies on the condition that the coupling coefficient between the nanocavity mode and the quantum dot exceeds the intrinsic decay rate of the nanocavity [17].
A good estimation of the failure mode of RC elements exhibiting a shear-flexural interaction relies on a good estimation of the flexural capacity (strength and ductility) and the shear capacity.
To test if the observed interaction relies on the SAM domain, two mutations, L73A and L75A, were introduced into the Ste50 SAM domain (Table 1).
Moreover, their interaction relies on the CPEB RNA-binding region of both human and worm counterparts (Hosoda et al. 2011; this work).
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CEO of Professional Science Editing for Scientists @ prosciediting.com