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In conclusion, this phase I trial was able to demonstrate that this intensive combination of cetuximab, oxaliplatin, 5-FU/FA and irinotecan in mCRC is feasible and has an acceptable toxicity profile in patients with a good PS.
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The standard treatment for ischaemic and non-ischaemic dilated cardiomyopathy is the intensive combination of medical and interventional treatments.
It is inferred from our findings that the intensive combination therapy with various immunosuppressive agents should be chosen for DM patients with ILD showing high serum PGRN levels, especially ≥200 ng/ml.
Although it remains possible that a similar response might be observed in some patients starting DMARD monotherapy, we suggest this rapid response may be a unique feature of intensive combination DMARDs (with multiple mechanisms of action) initiation in early RA, which is the RA population most responsive to therapeutic intervention.
This demographic selection occurred in the populations of gastric cancer patients treated with intensive combination chemotherapy regimens like the ECF (Tebbutt et al, 2002) or the weekly PELF.
Conclusions ADMIT demonstrates that it is both feasible and safe to modify multiple atherosclerotic disease risk factors effectively with intensive combination therapy in patients with PAD.
We used data from a published randomised controlled trial to assess whether responses to intensive combination treatments in early rheumatoid arthritis differ by ACPA status.
2015 Profile case Evaluation of treatment options N/A Meyfroidt S, Hulscher M, De Cock D, Van der Elst K, Joly J, Westhovens R, Verschueren P [56] A maximum difference scaling survey of barriers to intensive combination treatment strategies with glucocorticoids in early rheumatoid arthritis.
This stratification system was designed to identify high-risk patients who were likely to require more intensive combination chemotherapy.
Fifteen patients with relapsed osteosarcoma were treated with an intensive combination chemotherapy schedule.
High values were observed in lymphocytes from patients with lymphoma during intensive combination chemotherapy.
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