This includes validated non-synonymous somatic nucleotide substitutions, and likely homozygous deletions and multi-copy amplifications, as determined by the RAE algorithm (see Methods).
They included validated or potential therapeutic targets such as ANGPT1, ERBB2, FGFR1, GRB7, MYC, PAK1, PNMT, PROSC, SQLE, and STK3.
Additional measures included validated surveys of self-efficacy, social support, PPC, and diabetes self-care behavior.
The OR model also included validated treatment timing data from the British Dental Association (BDA) inquiry in 1999 [ 29].
The questionnaires included validated scales to assess turnover intention, work climate, work context factors, burnout, job satisfaction, and personality dimensions.
Efficacy parameters included validated clinical criteria from the ASAS working group [ 44] (namely BASDAI, BASFI, BASMI, and SF-36 for quality of life).
Evaluation included validated questionnaires like the Hospital Anxiety and Depression Scale (HADS) and the Brief Symptom Inventory 18 (BSI-18) for pre-post comparison of clinical outcomes.
Surveys were carried out 2 3 weeks and 18 months post-disaster, and included validated questionnaires on psychological distress, post-traumatic stress reactions and social functioning.
Participants from CRC screening trials were sent a questionnaire, which included validated measures on generic health-related QOL, generic anxiety and screen-specific anxiety.
This core Case Report Form battery consisted of basic patient, practice, and diagnostic information for screening and enrollment, along with a standard treatment-level form that included validated and reliable measures of safety, tolerability, and efficacy.
