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This impairs the ability of traders to smooth prices over time, resulting in lower efficiency and higher price variability.

We previously reported that autophagy-defective mutants cannot maintain the amino acid pool needed for protein synthesis, and this impairs the ability of cells to upregulate the expression of starvation-induced genes [4].

This impairs the ability of TFPI to neutralize both FXa and the tissue factor/FVIIa complex.

44, 45 The lipotoxicity due to toxic metabolites from FFA opens K-ATP channels 46 and this impairs the ability of cardiomyocytes to regulate calcium use, causing contractile dysfunction.

Importantly, this impairs the ability of ambulatory care professionals to provide for an appropriate continuation of post-hospital drug treatment and latently facilitates occurrence and perpetuation of secondary prescribing errors [ 12].

We have recently shown that ApoE in an AD-associated, isoform-specific manner impairs ApoE receptor recycling at central synapses (Chen et al., 2010b) and that this impairs the ability of ApoE receptor-dependent signals to prevent β-amyloid induced synaptic suppression (Durakoglugil et al., 2009).

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Importantly, this treatment eliminated the nutrient responsiveness of ilp5, permitting us to determine if this impaired the ability of DR to extend lifespan.

Furthermore, a cell impermeable copper chelator (bathocuproinedisulfonic acid) reduced vesicular copper accumulation in macrophages, and this impaired the ability of primary mouse macrophages to kill S. Typhimurium [ 111].

This reaction impairs the ability of platelets to produce a group of chemicals known as prostaglandins, which stimulate inflammation.

The assumption in question comprises two interrelated but separate proposals both awaiting confirmation: first, that acute stress alters the MDT in humans and second the deduction that this alteration impairs the ability to direct selective attention.

Maternal inheritance of this mutation impairs the ability of young mice to maintain body temperature.

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